# Testosterone Levels Associated with AFib

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## Email content

This Week in Internal Medicine News

Curated for

Alex Reed, MD

Journal of the Endocrine Society

Testosterone Levels Linked to AFib

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Radiology Business

Coronary Calcium Scans Not Beneficial for Everyone

U.S. Food and Drug Administration

FDA Approves Once-Weekly Insulin for Type 2 Diabetes Mellitus

Journal of the American College of Surgeons

How Medicare RVUs are Changing Across Physician Specialties

STAT

'Asian Glow' Is More Than a Social Inconvenience—and Clinicians Need to Say So

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JAMA Network Open

RSV Vaccine Effectiveness Among US Older Adults

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Annals of Internal Medicine

KDIGO 2026 Guideline Updates Iron Therapy Thresholds and ESA Targets for Anemia in CKD

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JAMA Internal Medicine

Does Fasting Duration Affect Routine Laboratory Tests?

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Doximity

This Week's Clinical Case from Doximity

63yo AA woman with HIV/ILD/PH, 2-year inflammatory arthritis, myositis (CK 675), Raynaud, parotitis. ANA 1:1280 speckled, strongly positive anti-Sm/RNP. Nephrotic proteinuria (UPCR 3.7 g/g) with preserved renal function. Mixed connective tissue disease with lupus nephritis features versus Sjögren's with immune complex GN.

What would be your most urgent next step after reviewing this patient's serologies and nephrotic-range proteinuria?

Start high-dose glucocorticoids plus mycophenolate immediately for presumed lupus nephritisObtain an urgent kidney biopsy before initiating definitive immunosuppressive therapy while treating symptomatically with hydroxychloroquine and low-dose prednisoneAttribute the findings primarily to HIV-associated nephropathy and optimize HIV management before additional rheumatologic treatmentPursue an extensive hematologic evaluation for monoclonal gammopathy first, delaying immunosuppression until completedRepeat autoimmune serologies and monitor closely, as chronic HIV can produce false-positive autoantibodiesExplore answer

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